Jon Darkow's Work

We found 56 items

#1 - Lactase Enzyme Simulation with Data Analysis

by Jon Darkow - 300510 runs
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#2 - Photosynthesis Model

by Jon Darkow - 81110 runs
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#3 - Evolution and Natural Selection

by Jon Darkow - 37792 runs
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#4 - Information Processing and Neurophysiology Model

by Jon Darkow - 35125 runs
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The main dependent variable measured in the model is the membrane potential (millivolts) of two different neurons in a series. You will be able to add excitatory and inhibitory neurotransmitters, and compare how these modulate electrical impulses of the two neurons. Additionally, you will be able to compare the effects of three neurotoxins: Tetrodotoxin, botulinum toxin, and sarin nerve gas. While extremely lethal, these toxins are very instructive in understanding neurons because of the specific way the toxins act. Each toxin modifies or inhibits a specific molecule in neurons that help process and transmit information.

#5 - Lactase with Variable Sample Sizes

by Jon Darkow - 19348 runs
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Arrayed Lactase Model

#6 - Population dynamics of white footed mouse

by Jon Darkow - 46075 runs
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#7 - Lac Operon with Monod Bump

by Jon Darkow - 13954 runs
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#8 - Evolution of LAP Allele in Mussels

by Jon Darkow - 15297 runs
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#9 - Cellular Respiration Accounting Model

by Jon Darkow - 13211 runs
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The purpose of the model is to understand how glucose is metabolized, and how the energy stored in its chemical bonds is transfered.

#10 - Recombination and Gene Linkage

by Jon Darkow - 11626 runs
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#11 - White-Eyed Genetics

by Jon Darkow - 5129 runs
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White-eyed is an allele that results in a fly white eyes. Wild-type variants have red eyes. The goal of this simulation is to determine the pattern of inheritance for the white-eyed phenotype. Is yellow body dominant or recessive? Sex-linked or autosomal? Complete, incomplete, or codominant?

#12 - Photosynthesis with Variable Sample Sizes

by Jon Darkow - 3072 runs - 13 downloads
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Sample sizes of Photosynthesis stocks in an array

#13 - Water Potential and Osmosis

by Jon Darkow - 9590 runs
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Factors that affect the flow across a semi-permeable membrane.

#14 - Apterous Genetics

by Jon Darkow - 22066 runs
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Apterous is an allele that results in a fly without wings. Wild-type variants have normally functioning wings. The goal of this simulation is to determine the pattern of inheritance for the apterous phenotype. Is apterous dominant or recessive? Sex-linked or autosomal? Complete, incomplete, or codominant?

#15 - Extinction Vortex

by Jon Darkow - 4599 runs
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#16 - Transformation Simulation

by Jon Darkow - 4476 runs
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Simulation allows students to test the transformation principle. Two major goals of the experiment are: 1. Allow users to see that supernatant from heat-killed bacteria can transform the genes of another bacterium. 2. What transforms the inheritance of the bacteria is DNA, not RNA or proteins.

#17 - Diffusion of a Spherical Cell

by Jon Darkow - 2504 runs
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Why are cells small? This model allows users to see how the size of a sphere affects the rate of diffusion.

#18 - Steady State in Freshwater Ecosystems

by Jon Darkow - 12112 runs
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#19 - Evolving Bits

by Jon Darkow - 1305 runs
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Diversity and selection for the basis of evolution. This simple model tries to illustrate these concepts.

#20 - Growth Factors, Cyclins, and Cancer

by Jon Darkow - 19276 runs
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Explores the feedback loops that regulate the cell cycle. Model focuses on manipulating stimuli (growth factors), to stimulate the cell cycle feedback loops.

#21 - HPV and Adaptive Immune Response

by Jon Darkow - 3037 runs
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#22 - Evolution

by Jon Darkow - 1331 runs
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Evolution of Populations: Genetic Drift, Natural Selection, and Mutations

#23 - Tryptophan Operon: A repressible system

by Jon Darkow - 6216 runs
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#24 - Circadian Clock in the Mouse

by Jon Darkow - 2417 runs
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Transcriptional Translational Feedback Loop in the Mouse

#25 - Tick Tock: The Biological Clock and Circadian Rhythm

by Jon Darkow - 738 runs
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Explore gene expression of the transcriptional-translational feedback loop (TTFL) of the mouse circadian rhythm.

#26 - Pattern with recessive single band

by Jon Darkow - 9967 runs
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#27 - Phenology of the Karner Blue Butterfly

by Jon Darkow - 1439 runs
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Karner Blue butterfly is an endangered species. Habitat loss and climate change are contributing factors to the reduction in the butterflies' population sizes. Climate change can alter the timing of lifecycles. When climate change disproportionally affects the timing of life cycles of species in an ecosystem asynchrony within a food web occurs.

#28 - Tesing Unknown Enzymes

by Jon Darkow - 874 runs
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#29 - Logistic Growth Model and the Butterfly Effect

by Jon Darkow - 562 runs
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Model allows users to test the starting population size (N), the carrying capacity of the population (K), and the intrinsic rate of growth (r max). Iterations are discrete, not continuous.

#30 - Neurophysiology and Neurotoxicity

by Jon Darkow - 6786 runs
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The main dependent variable measured in the model is the membrane potential (millivolts) of a motor neuron and the muscle fiber it innervates. You will be able to add excitatory and inhibitory neurotransmitters, and compare how neurotransmitters modulate the electrical impulses of the motor neuron and the muscle fiber. Additionally, you will be able to compare the effects of four neurotoxins: Tetrodotoxin, botulinum toxin, sarin nerve gas, and VX. While extremely lethal, these toxins are very instructive in understanding neurons because of the specific way the toxins act. Each toxin modifies or inhibits a specific molecule in neurons that help process and transmit information.

#31 - Lactose Operon: An Inducible System

by Jon Darkow - 14538 runs
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In this simulation users explore the negative feedback system of the Lactose Operon found in bacteria. Lactose induces the system by inhibiting and inhibitor.

#32 - Chaos Theory: Strange Attractor

by Jon Darkow - 188 runs
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Manipulate the main variables of the Lorenz equation.

#33 - Evolution: Grants Finches

by Jon Darkow - 520 runs
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Models the effects on population sizes of ground finches with different beak sizes in response to different amounts of annual precipitation.

#34 - Logistic Growth Model

by Jon Darkow - 165 downloads
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#35 - System Dynamics of Carbon Budget

by Jon Darkow - 437 runs
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Simulation of the system dynamics of the global carbon dioxide budget based on the work on systems dynamics based on John Sternman (MIT) and Krytyna Stave (University of Nebraska)

#36 - Exponential Growth in Population - AF

by Jon Darkow - 97 downloads
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Chapter 2: Modeling the Environment

#37 - Catastrophic Regime Change in Aquatic Ecosystems

by Jon Darkow - 232 runs
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#38 - Chapter 2: Population Growth

by Jon Darkow - 80 downloads
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Chapter 2 introduction

#39 - Cellular Respiration Inquiry

by Jon Darkow - 12135 runs
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Model of the dynamics of the metabolism of one mole of glucose. Randomness is built into the computations.

#40 - Evolving Bits N=40

by Jon Darkow - 342 runs
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#41 - Limiting Nutrients in Aquatic Ecosystems

by Jon Darkow - 10377 runs
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Experiment with a variety of nutrients that are limited by different degrees in four different ecosystems.

#43 - Chapter 2.12

by Jon Darkow - 66 downloads
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#44 - Thyroid Hormone - Negative Feedback

by Jon Darkow - 5169 runs
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#45 - Pattern of Inheritance and Gel Electrophoresis

by Jon Darkow - 54 runs
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#46 - The dynamics of photosynthesis - variable sample size

by Jon Darkow - 35 runs
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The dynamics of photosynthesis - variable sample size

#47 - Stock, Inflow, and Outflow with Atrazine

by Jon Darkow - 32 runs
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Simple stock and flow diagram. Flows linear.

#48 - Fruit Fly Choice

by Jon Darkow - 90 runs
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Simulation to model random behavior in a fruit fly choice chamber

#49 - Fruit Fly with variable sample size

by Jon Darkow - 36 runs
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#50 - Simple Genetics

by Jon Darkow - 1603 runs
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#51 - Carbon in the Atmosphere - Graphic Input constant

by Jon Darkow - 22 runs
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#52 - Oxytocin and Child Birth

by Jon Darkow - 9765 runs
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#53 - GLUT and Insulin

by Jon Darkow - 6 runs
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#54 - Photosynthesis Simulation with Variance

by Jon Darkow - 81 runs
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#55 - Cardiovascular Model

by Jon Darkow - 0 runs
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#56 - Grant Finches Mobile

by Jon Darkow - 5 runs
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