Jon Darkow's Work

We found 60 items

#1 - Lactase Enzyme Simulation with Data Analysis

by Jon Darkow - 780029 runs
Play

#2 - Photosynthesis Model

by Jon Darkow - 117707 runs
Play

#3 - Evolution and Natural Selection

by Jon Darkow - 83153 runs
Play

#4 - Population dynamics of white footed mouse

by Jon Darkow - 72965 runs
Play

#5 - Information Processing and Neurophysiology Model

by Jon Darkow - 60595 runs
Play

The main dependent variable measured in the model is the membrane potential (millivolts) of two different neurons in a series. You will be able to add excitatory and inhibitory neurotransmitters, and compare how these modulate electrical impulses of the two neurons. Additionally, you will be able to compare the effects of three neurotoxins: Tetrodotoxin, botulinum toxin, and sarin nerve gas. While extremely lethal, these toxins are very instructive in understanding neurons because of the specific way the toxins act. Each toxin modifies or inhibits a specific molecule in neurons that help process and transmit information.

#6 - Lac Operon with Monod Bump

by Jon Darkow - 32843 runs
Play

#7 - Evolution of LAP Allele in Mussels

by Jon Darkow - 23445 runs
Play

#8 - Lactase with Variable Sample Sizes

by Jon Darkow - 40377 runs
Play

Arrayed Lactase Model

#9 - Lactose Operon: An Inducible System

by Jon Darkow - 21898 runs
Play

In this simulation users explore the negative feedback system of the Lactose Operon found in bacteria. Lactose induces the system by inhibiting and inhibitor.

#10 - Cellular Respiration Accounting Model

by Jon Darkow - 25246 runs
Play

The purpose of the model is to understand how glucose is metabolized, and how the energy stored in its chemical bonds is transfered.

#11 - Limiting Nutrients in Aquatic Ecosystems

by Jon Darkow - 15697 runs
Play

Experiment with a variety of nutrients that are limited by different degrees in four different ecosystems.

#12 - Water Potential and Osmosis

by Jon Darkow - 23211 runs
Play

Factors that affect the flow across a semi-permeable membrane.

#13 - Diffusion of a Spherical Cell

by Jon Darkow - 9641 runs
Play

Why are cells small? This model allows users to see how the size of a sphere affects the rate of diffusion.

#14 - Photosynthesis with Variable Sample Sizes

by Jon Darkow - 7561 runs - 20 downloads
Download Model Play

Sample sizes of Photosynthesis stocks in an array

#15 - Thyroid Hormone - Negative Feedback

by Jon Darkow - 7029 runs
Play

#16 - Recombination and Gene Linkage

by Jon Darkow - 25821 runs
Play

#17 - Transformation Simulation

by Jon Darkow - 8540 runs
Play

Simulation allows students to test the transformation principle. Two major goals of the experiment are: 1. Allow users to see that supernatant from heat-killed bacteria can transform the genes of another bacterium. 2. What transforms the inheritance of the bacteria is DNA, not RNA or proteins.

#18 - White-Eyed Genetics

by Jon Darkow - 17669 runs
Play

White-eyed is an allele that results in a fly white eyes. Wild-type variants have red eyes. The goal of this simulation is to determine the pattern of inheritance for the white-eyed phenotype. Is yellow body dominant or recessive? Sex-linked or autosomal? Complete, incomplete, or codominant?

#19 - Apterous Genetics

by Jon Darkow - 57641 runs
Play

Apterous is an allele that results in a fly without wings. Wild-type variants have normally functioning wings. The goal of this simulation is to determine the pattern of inheritance for the apterous phenotype. Is apterous dominant or recessive? Sex-linked or autosomal? Complete, incomplete, or codominant?

#20 - Extinction Vortex

by Jon Darkow - 5387 runs
Play

#21 - Steady State in Freshwater Ecosystems

by Jon Darkow - 12287 runs
Play

#22 - Evolving Bits

by Jon Darkow - 1320 runs
Play

Diversity and selection for the basis of evolution. This simple model tries to illustrate these concepts.

#23 - Evolution with Heterozygous Advantage

by Jon Darkow - 1768 runs
Play

Evolution of Populations: Genetic Drift, Natural Selection, and Mutations

#24 - Growth Factors, Cyclins, and Cancer

by Jon Darkow - 44952 runs
Play

Explores the feedback loops that regulate the cell cycle. Model focuses on manipulating stimuli (growth factors), to stimulate the cell cycle feedback loops.

#25 - HPV and Adaptive Immune Response

by Jon Darkow - 4020 runs
Play

#26 - Tryptophan Operon: A repressible system

by Jon Darkow - 11808 runs
Play

#27 - Guppy Evolution

by Jon Darkow - 1381 runs
Play

#28 - Circadian Clock in the Mouse

by Jon Darkow - 6030 runs
Play

Transcriptional Translational Feedback Loop in the Mouse

#29 - Tick Tock: The Biological Clock and Circadian Rhythm

by Jon Darkow - 790 runs
Play

Explore gene expression of the transcriptional-translational feedback loop (TTFL) of the mouse circadian rhythm.

#30 - Pattern with recessive single band

by Jon Darkow - 13622 runs
Play

#31 - Phenology of the Karner Blue Butterfly

by Jon Darkow - 1636 runs
Play

Karner Blue butterfly is an endangered species. Habitat loss and climate change are contributing factors to the reduction in the butterflies' population sizes. Climate change can alter the timing of lifecycles. When climate change disproportionally affects the timing of life cycles of species in an ecosystem asynchrony within a food web occurs.

#32 - Evolving Bits N=40

by Jon Darkow - 883 runs
Play

#33 - Tesing Unknown Enzymes

by Jon Darkow - 2707 runs
Play

#34 - Logistic Growth Model and the Butterfly Effect

by Jon Darkow - 694 runs
Play

Model allows users to test the starting population size (N), the carrying capacity of the population (K), and the intrinsic rate of growth (r max). Iterations are discrete, not continuous.

#35 - Neurophysiology and Neurotoxicity

by Jon Darkow - 13288 runs
Play

The main dependent variable measured in the model is the membrane potential (millivolts) of a motor neuron and the muscle fiber it innervates. You will be able to add excitatory and inhibitory neurotransmitters, and compare how neurotransmitters modulate the electrical impulses of the motor neuron and the muscle fiber. Additionally, you will be able to compare the effects of four neurotoxins: Tetrodotoxin, botulinum toxin, sarin nerve gas, and VX. While extremely lethal, these toxins are very instructive in understanding neurons because of the specific way the toxins act. Each toxin modifies or inhibits a specific molecule in neurons that help process and transmit information.

#36 - Logistic Growth Model

by Jon Darkow - 275 downloads
View

#37 - Chaos Theory: Strange Attractor

by Jon Darkow - 325 runs
Play

Manipulate the main variables of the Lorenz equation.

#38 - Exponential Growth in Population - AF

by Jon Darkow - 206 downloads
View

Chapter 2: Modeling the Environment

#39 - Evolution: Grants Finches

by Jon Darkow - 579 runs
Play

Models the effects on population sizes of ground finches with different beak sizes in response to different amounts of annual precipitation.

#40 - System Dynamics of Carbon Budget

by Jon Darkow - 639 runs
Play

Simulation of the system dynamics of the global carbon dioxide budget based on the work on systems dynamics based on John Sternman (MIT) and Krytyna Stave (University of Nebraska)

#41 - Genotyping with Electrophoresis

by Jon Darkow - 1302 runs
Play

#42 - Enzyme Diversity: Enzymes, Products, and Substrates

by Jon Darkow - 23575 runs
Play

#43 - Chapter 2: Population Growth

by Jon Darkow - 128 downloads
View

Chapter 2 introduction

#44 - Chapter 2.12

by Jon Darkow - 109 downloads
View

#45 - Catastrophic Regime Change in Aquatic Ecosystems

by Jon Darkow - 973 runs
Play

#46 - Cellular Respiration Inquiry

by Jon Darkow - 28711 runs
Play

Model of the dynamics of the metabolism of one mole of glucose. Randomness is built into the computations.

#48 - Beta Cell Membrane Transport - Insulin Regulation

by Jon Darkow - 211 runs
Play

#49 - The dynamics of photosynthesis - variable sample size

by Jon Darkow - 37 runs
Play

The dynamics of photosynthesis - variable sample size

#50 - Stock, Inflow, and Outflow with Atrazine

by Jon Darkow - 39 runs
Play

Simple stock and flow diagram. Flows linear.

#51 - Beta Cell Simulation - Split story

by Jon Darkow - 1590 runs
Play

#52 - Fruit Fly Choice

by Jon Darkow - 123 runs
Play

Simulation to model random behavior in a fruit fly choice chamber

#53 - Photosynthesis Simulation with Variance

by Jon Darkow - 31893 runs
Play

#54 - Fruit Fly with variable sample size

by Jon Darkow - 39 runs
Play

#55 - Simple Genetics

by Jon Darkow - 14734 runs
Play

#56 - Carbon in the Atmosphere - Graphic Input constant

by Jon Darkow - 25 runs
Play

#57 - Oxytocin and Child Birth

by Jon Darkow - 15771 runs
Play

#58 - GLUT and Insulin

by Jon Darkow - 9 runs
Play

#59 - Grant Finches Mobile

by Jon Darkow - 10 runs
Play

#60 - Cardiovascular Model

by Jon Darkow - 0 runs
Play