Jon Darkow's Work

We found 59 items

#1 - Lactase Enzyme Simulation with Data Analysis

by Jon Darkow - 358129 runs
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#2 - Photosynthesis Model

by Jon Darkow - 82297 runs
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#3 - Evolution and Natural Selection

by Jon Darkow - 51575 runs
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#4 - Information Processing and Neurophysiology Model

by Jon Darkow - 35838 runs
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The main dependent variable measured in the model is the membrane potential (millivolts) of two different neurons in a series. You will be able to add excitatory and inhibitory neurotransmitters, and compare how these modulate electrical impulses of the two neurons. Additionally, you will be able to compare the effects of three neurotoxins: Tetrodotoxin, botulinum toxin, and sarin nerve gas. While extremely lethal, these toxins are very instructive in understanding neurons because of the specific way the toxins act. Each toxin modifies or inhibits a specific molecule in neurons that help process and transmit information.

#5 - Lactase with Variable Sample Sizes

by Jon Darkow - 20838 runs
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Arrayed Lactase Model

#6 - Population dynamics of white footed mouse

by Jon Darkow - 49149 runs
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#7 - Lac Operon with Monod Bump

by Jon Darkow - 14065 runs
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#8 - Evolution of LAP Allele in Mussels

by Jon Darkow - 15372 runs
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#9 - Water Potential and Osmosis

by Jon Darkow - 10883 runs
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Factors that affect the flow across a semi-permeable membrane.

#10 - Cellular Respiration Accounting Model

by Jon Darkow - 13301 runs
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The purpose of the model is to understand how glucose is metabolized, and how the energy stored in its chemical bonds is transfered.

#11 - Recombination and Gene Linkage

by Jon Darkow - 11645 runs
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#12 - White-Eyed Genetics

by Jon Darkow - 5172 runs
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White-eyed is an allele that results in a fly white eyes. Wild-type variants have red eyes. The goal of this simulation is to determine the pattern of inheritance for the white-eyed phenotype. Is yellow body dominant or recessive? Sex-linked or autosomal? Complete, incomplete, or codominant?

#13 - Photosynthesis with Variable Sample Sizes

by Jon Darkow - 3097 runs - 14 downloads
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Sample sizes of Photosynthesis stocks in an array

#14 - Apterous Genetics

by Jon Darkow - 22238 runs
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Apterous is an allele that results in a fly without wings. Wild-type variants have normally functioning wings. The goal of this simulation is to determine the pattern of inheritance for the apterous phenotype. Is apterous dominant or recessive? Sex-linked or autosomal? Complete, incomplete, or codominant?

#15 - Extinction Vortex

by Jon Darkow - 4617 runs
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#16 - Transformation Simulation

by Jon Darkow - 4547 runs
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Simulation allows students to test the transformation principle. Two major goals of the experiment are: 1. Allow users to see that supernatant from heat-killed bacteria can transform the genes of another bacterium. 2. What transforms the inheritance of the bacteria is DNA, not RNA or proteins.

#17 - Diffusion of a Spherical Cell

by Jon Darkow - 8816 runs
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Why are cells small? This model allows users to see how the size of a sphere affects the rate of diffusion.

#18 - Steady State in Freshwater Ecosystems

by Jon Darkow - 12127 runs
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#19 - Evolving Bits

by Jon Darkow - 1306 runs
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Diversity and selection for the basis of evolution. This simple model tries to illustrate these concepts.

#20 - Evolution with Heterozygous Advantage

by Jon Darkow - 1433 runs
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Evolution of Populations: Genetic Drift, Natural Selection, and Mutations

#21 - Growth Factors, Cyclins, and Cancer

by Jon Darkow - 19310 runs
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Explores the feedback loops that regulate the cell cycle. Model focuses on manipulating stimuli (growth factors), to stimulate the cell cycle feedback loops.

#22 - HPV and Adaptive Immune Response

by Jon Darkow - 3067 runs
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#23 - Tryptophan Operon: A repressible system

by Jon Darkow - 6228 runs
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#24 - Circadian Clock in the Mouse

by Jon Darkow - 2451 runs
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Transcriptional Translational Feedback Loop in the Mouse

#25 - Tick Tock: The Biological Clock and Circadian Rhythm

by Jon Darkow - 739 runs
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Explore gene expression of the transcriptional-translational feedback loop (TTFL) of the mouse circadian rhythm.

#26 - Pattern with recessive single band

by Jon Darkow - 9990 runs
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#27 - Phenology of the Karner Blue Butterfly

by Jon Darkow - 1586 runs
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Karner Blue butterfly is an endangered species. Habitat loss and climate change are contributing factors to the reduction in the butterflies' population sizes. Climate change can alter the timing of lifecycles. When climate change disproportionally affects the timing of life cycles of species in an ecosystem asynchrony within a food web occurs.

#28 - Tesing Unknown Enzymes

by Jon Darkow - 917 runs
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#29 - Logistic Growth Model and the Butterfly Effect

by Jon Darkow - 597 runs
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Model allows users to test the starting population size (N), the carrying capacity of the population (K), and the intrinsic rate of growth (r max). Iterations are discrete, not continuous.

#30 - Neurophysiology and Neurotoxicity

by Jon Darkow - 6834 runs
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The main dependent variable measured in the model is the membrane potential (millivolts) of a motor neuron and the muscle fiber it innervates. You will be able to add excitatory and inhibitory neurotransmitters, and compare how neurotransmitters modulate the electrical impulses of the motor neuron and the muscle fiber. Additionally, you will be able to compare the effects of four neurotoxins: Tetrodotoxin, botulinum toxin, sarin nerve gas, and VX. While extremely lethal, these toxins are very instructive in understanding neurons because of the specific way the toxins act. Each toxin modifies or inhibits a specific molecule in neurons that help process and transmit information.

#31 - Lactose Operon: An Inducible System

by Jon Darkow - 14539 runs
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In this simulation users explore the negative feedback system of the Lactose Operon found in bacteria. Lactose induces the system by inhibiting and inhibitor.

#32 - Chaos Theory: Strange Attractor

by Jon Darkow - 260 runs
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Manipulate the main variables of the Lorenz equation.

#33 - Logistic Growth Model

by Jon Darkow - 202 downloads
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#34 - Evolution: Grants Finches

by Jon Darkow - 530 runs
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Models the effects on population sizes of ground finches with different beak sizes in response to different amounts of annual precipitation.

#35 - System Dynamics of Carbon Budget

by Jon Darkow - 465 runs
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Simulation of the system dynamics of the global carbon dioxide budget based on the work on systems dynamics based on John Sternman (MIT) and Krytyna Stave (University of Nebraska)

#36 - Exponential Growth in Population - AF

by Jon Darkow - 130 downloads
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Chapter 2: Modeling the Environment

#37 - Enzyme Diversity: Enzymes, Products, and Substrates

by Jon Darkow - 898 runs
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#38 - Catastrophic Regime Change in Aquatic Ecosystems

by Jon Darkow - 267 runs
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#39 - Chapter 2: Population Growth

by Jon Darkow - 95 downloads
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Chapter 2 introduction

#40 - Cellular Respiration Inquiry

by Jon Darkow - 12175 runs
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Model of the dynamics of the metabolism of one mole of glucose. Randomness is built into the computations.

#41 - Chapter 2.12

by Jon Darkow - 85 downloads
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#42 - Limiting Nutrients in Aquatic Ecosystems

by Jon Darkow - 11191 runs
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Experiment with a variety of nutrients that are limited by different degrees in four different ecosystems.

#43 - Evolving Bits N=40

by Jon Darkow - 358 runs
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#45 - Beta Cell Membrane Transport - Insulin Regulation

by Jon Darkow - 209 runs
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#46 - Thyroid Hormone - Negative Feedback

by Jon Darkow - 5178 runs
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#47 - Pattern of Inheritance and Gel Electrophoresis

by Jon Darkow - 55 runs
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#48 - The dynamics of photosynthesis - variable sample size

by Jon Darkow - 35 runs
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The dynamics of photosynthesis - variable sample size

#49 - Stock, Inflow, and Outflow with Atrazine

by Jon Darkow - 34 runs
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Simple stock and flow diagram. Flows linear.

#50 - Fruit Fly Choice

by Jon Darkow - 99 runs
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Simulation to model random behavior in a fruit fly choice chamber

#51 - Beta Cell Simulation - Split story

by Jon Darkow - 41 runs
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#52 - Fruit Fly with variable sample size

by Jon Darkow - 37 runs
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#53 - Simple Genetics

by Jon Darkow - 1640 runs
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#54 - Carbon in the Atmosphere - Graphic Input constant

by Jon Darkow - 23 runs
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#55 - Oxytocin and Child Birth

by Jon Darkow - 9976 runs
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#56 - GLUT and Insulin

by Jon Darkow - 6 runs
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#57 - Photosynthesis Simulation with Variance

by Jon Darkow - 87 runs
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#58 - Cardiovascular Model

by Jon Darkow - 0 runs
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#59 - Grant Finches Mobile

by Jon Darkow - 7 runs
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