srrz63's Work

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#1 - SR interaction of slbo and trbl

by srrz63 - 110 downloads

Model of the interaction between Slbo and Trbl. C/EBP encoded by Slbo binds Trbl and is subsequently tagged by uiquitination. This interaction also changes the function of the pseudokinase domain of Trbl. In result, Trbl becomes susceptible to small molecule binding and is degraded.